@article{186291, keywords = {Humans, Cell Line, Tumor, Breast Neoplasms, Epithelial-Mesenchymal Transition, Cadherins}, author = {Minhong Shen and Yibin Kang}, title = {Role Reversal: A Pro-metastatic Function of E-Cadherin}, abstract = {

Carcinoma cells often acquire mobility and invasiveness by undergoing epithelial-to-mesenchymal transition, and yet most metastatic lesions remain epithelial in nature. Recently, in Nature, Padmanaban et\ al. (2019) demonstrated that the quintessential epithelial marker E-cadherin promotes metastasis of invasive ductal breast carcinoma by enhancing the survival of tumor cells.

}, year = {2019}, journal = {Dev Cell}, volume = {51}, pages = {417-419}, month = {11/2019}, issn = {1878-1551}, doi = {10.1016/j.devcel.2019.10.028}, language = {eng}, }