@article{204156, keywords = {Humans, Sequence Analysis, RNA, Cell Lineage, Pancreatic Neoplasms, Whole Exome Sequencing}, author = {Eunmi Lee and Yibin Kang}, title = {Lineage tracing reveals metastatic dynamics}, abstract = {
Combining single-cell lineage tracing with RNA sequencing has provided unprecedented opportunities to prospectively explore metastatic dynamics in\ vivo. In this issue of Cancer Cell, Simeonov et\ al. developed the macsGESTALT lineage recording system to reveal that hybrid EMT states and S100 expression are associated with elevated metastatic abilities in a pancreatic cancer model.
}, year = {2021}, journal = {Cancer Cell}, volume = {39}, pages = {1050-1052}, month = {08/2021}, issn = {1878-3686}, doi = {10.1016/j.ccell.2021.06.005}, language = {eng}, }