@article{204181, keywords = {Humans, Immunotherapy, Triple Negative Breast Neoplasms, Immunity, Cellular}, author = {Yong Tang and Yibin Kang}, title = {Microbial metabolite as icebreaker for immunotherapy}, abstract = {
Immunotherapy has limited success in triple-negative breast cancer (TNBC). In this issue of Cell Metabolism, Wang et\ al. found that microbial metabolite TMAO boosts CD8 T\ cell-mediated antitumor immunity by inducing pyroptosis in tumor cells, enhancing the efficacy of immunotherapy in TNBC (Wang et\ al., 2022).
}, year = {2022}, journal = {Cell Metab}, volume = {34}, pages = {506-507}, month = {04/2022}, issn = {1932-7420}, doi = {10.1016/j.cmet.2022.03.003}, language = {eng}, }