@article{87891,
  author = {Toni Celi{\`a}-Terrassa and Yibin Kang},
  title = {Mouse genomic screen reveals novel host regulator of metastasis},
  abstract = {<p>Tumor cells have to overcome challenges in the host tissue microenvironment to metastasize successfully to distant organs. In a recent Nature study, a genome-wide functional screen demonstrated that deficiency of the sphingosine-1-phoshate (S1P) transporter gene Spns2 in endothelium increased immune-mediated cell killing by T cells and natural killer (NK) cells, thereby suppressing metastatic colonization.</p>
},
  year = {2017},
  journal = {Genome Biol},
  volume = {18},
  pages = {31},
  month = {02/2017},
  issn = {1474-760X},
  doi = {10.1186/s13059-017-1170-x},
  language = {eng},
}