@article{87971,
  keywords = {Animals, Humans, MicroRNAs, Female, Male, Gene Expression Regulation, Neoplastic, Gene Silencing, Tumor Microenvironment, Brain Neoplasms, Exosomes, PTEN Phosphohydrolase},
  author = {Ma{\v s}a Ale{\v c}kovi{\'c} and Yibin Kang},
  title = {Welcoming Treat: Astrocyte-Derived Exosomes Induce PTEN Suppression to Foster Brain Metastasis.},
  abstract = {<p>Metastasis to distant organs depends on pathological crosstalk between tumor cells and various tissue-specific stromal components. Zhang and colleagues recently demonstrated that astrocyte-derived exosomal miR-19a reversibly downregulated PTEN expression in cancer cells, thereby increasing their CCL2 secretion and recruitment of myeloid cell to promote brain metastasis.</p>
},
  year = {2015},
  journal = {Cancer Cell},
  volume = {28},
  pages = {554-6},
  month = {11/2015},
  issn = {1878-3686},
  doi = {10.1016/j.ccell.2015.10.010},
  language = {eng},
}