@article{88076, keywords = {Animals, Humans, RNA, Long Noncoding, Male, Transforming Growth Factor beta, Liver Neoplasms, Carcinoma, Hepatocellular}, author = {Wenyang Li and Yibin Kang}, title = {A new Lnc in metastasis: long noncoding RNA mediates the prometastatic functions of TGF-β.}, abstract = {

TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.

}, year = {2014}, journal = {Cancer Cell}, volume = {25}, pages = {557-9}, month = {05/2014}, issn = {1878-3686}, doi = {10.1016/j.ccr.2014.04.014}, language = {eng}, }