MicroRNA-711 is a prognostic factor for poor overall survival and has an oncogenic role in breast cancer.
Publication Year
2016
Type
Journal Article
Abstract
MicroRNAs are important in cancer development and progression. In the present study, the clinical significance and function of microRNA-711 (miR-711) expression in breast cancer were investigated. The expression level of miR-711 was analyzed in breast cancer tissue samples using reverse transcription-quantitative polymerase chain reaction. Cell proliferation, colony formation, apoptosis and Transwell assays were performed in breast cancer cell lines transfected with miR-711 mimics or inhibitors, or control sequence. miR-711 was found to be upregulated in 30 formalin-fixed paraffin-embedded breast cancer tissue samples compared with paired non-cancerous breast tissues (P
Journal
Oncol Lett
Volume
11
Issue
3
Pages
2155-2163
Date Published
03/2016
ISSN Number
1792-1074
Alternate Journal
Oncol Lett
PMID
26998141